The Benefits of NAD+

The Benefits of NAD+

Would you be surprised to know that the cardiovascular system, memory, eyesight, and a person’s mood all rely on the same enzyme to function properly?

That’s right. These systems, and many more, rely on the actions of nicotinamide adenine dinucleotide (NAD+), a key coenzyme found in all living cells.

However, NAD+ production can slow down as we get older, wreaking havoc across the body.

Luckily, there’s a solution to keep the enzymes strong and the body aging with grace.

NAD+ IV therapy is an intravenous solution that directly injects NAD into the body so that it can begin addressing any deficiencies and help the body thrive.

NAD+ Benefits

The benefits of NAD+ are numerous, and they can include:

Improved Cognitive Function

Your cognitive function often declines with age, resulting in brain fog, memory loss, and difficulty concentrating. If NAD+ levels are low, these symptoms can be exacerbated.

This is because the body uses NAD+ and mitochondria to convert glucose into metabolic energy, which gives energy to the brain cells. If you have low NAD+, your brain cells are left without enough energy to function properly.

Studies have found that supplementing with NAD+ helps combat neuroinflammation and mitochondrial damage, further assisting in its improvements to cognitive function and oxidative stress.

Fights Fatigue

For those suffering from physical and mental fatigue, NAD+ supplementation can assist with the process of obtaining energy from food, raising energy levels.

A review looking to better understand the relationship between NAD+ and chronic fatigue syndrome examined the idea that impaired tryptophan metabolism plays a role in the development of chronic fatigue syndrome. This is partly because tryptophan, an amino acid, is a precursor for NAD+. So, if tryptophan is not metabolized, NAD+ production lowers, which can lead to fatigue.

Therefore, raising levels of NAD+ may help to overcome the debilitating symptoms of chronic fatigue syndrome and improve quality of life.

Promotes Healthy Aging

We all want to age gracefully, and NAD+ can help with this.

NAD+ can activate the class of enzymes called sirtuins, which studies have shown to improve overall health and life span. Their benefits may include boosting stress resistance, repairing damaged DNA, and reducing inflammation, which are all components that promote healthy aging.

Lowers Heart Disease Risk

As the body ages, the arteries can undergo changes that negatively affect the body. The thickening and stiffening of blood vessels like the aorta can raise blood pressure and make the heart work harder.

However, studies have shown that raising NAD+ levels helps to reduce aorta stiffness, which lowers systolic blood pressure in adults who have been at risk of high blood pressure.

By reducing high blood pressure, NAD+ therapy can reduce the risk of heart disease or other cardiovascular problems.

May Protect Against Cancer

Some factors which are linked to cancer development include oxidative stress and DNA damage. However, studies have found that high NAD+ levels, achieved through NAD+ IV therapy, help protect against these factors, which may lower cancer risk.

Eases Anxiety

NAD+ therapy may also help to alleviate the symptoms of anxiety through its activation of a specific type of sirtuin enzyme that bolsters low serotonin levels. Researchers have found that low serotonin levels can contribute to anxiety, and since sirtuins depend on NAD+ to function, supplementing with NAD+ may help ease anxiety symptoms.

Try NAD+ IV Therapy

With the many benefits of NAD+ spanning from protective qualities to mood boosters, it is clear that this powerful coenzyme infusion offers something for everyone.

To get the most benefit from NAD+, try NAD+ IV Therapy for a fast and direct infusion that quickly returns balance to your body.


Zhao, Y., Zhang, J., Zheng, Y., Zhang, Y., Zhang, X., & Wang, H. et al. (2021). NAD+ improves cognitive function and reduces neuroinflammation by ameliorating mitochondrial damage and decreasing ROS production in chronic cerebral hypoperfusion models through Sirt1/PGC-1α pathway. Journal Of Neuroinflammation, 18(1). doi: 10.1186/s12974-021-02250-8

Sweeney, G., & Song, J. (2016). The association between PGC-1α and Alzheimer’s disease. Anatomy &Amp; Cell Biology, 49(1), 1. doi: 10.5115/acb.2016.49.1.1

Dehhaghi, M., Panahi, H., Kavyani, B., Heng, B., Tan, V., Braidy, N., & Guillemin, G. (2022). The Role of Kynurenine Pathway and NAD+ Metabolism in Myalgic Encephalomyelitis/Chronic Fatigue Syndrome. Aging And Disease, 13(3), 698. doi: 10.14336/ad.2021.0824

Satoh, A., Stein, L., & Imai, S. (2011). The Role of Mammalian Sirtuins in the Regulation of Metabolism, Aging, and Longevity. Histone Deacetylases: The Biology And Clinical Implication, 125-162. doi: 10.1007/978-3-642-21631-2_7

Martens, C., Denman, B., Mazzo, M., Armstrong, M., Reisdorph, N., & McQueen, M. et al. (2017). NAA1 NICOTINAMIDE RIBOSIDE SUPPLEMENTATION REDUCES AORTIC STIFFNESS AND BLOOD PRESSURE IN MIDDLE-AGED AND OLDER ADULTS. Artery Research, 20(C), 49. doi: 10.1016/j.artres.2017.10.021

Son, M., Ryu, J., Kim, J., Kwon, Y., Chung, K., Mun, S., & Cho, Y. (2017). Upregulation of mitochondrial NAD+ levels impairs the clonogenicity of SSEA1+ glioblastoma tumor-initiating cells. Experimental &Amp; Molecular Medicine, 49(6), e344-e344. doi: 10.1038/emm.2017.74

Song, J., & Kim, J. (2016). Role of Sirtuins in Linking Metabolic Syndrome with Depression. Frontiers In Cellular Neuroscience, 10. doi: 10.3389/fncel.2016.00086

Braidy, N., Villalva, M., & Eeden, S. (2020). Sobriety and Satiety: Is NAD+ the Answer?. Antioxidants, 9(5), 425. doi: 10.3390/antiox9050425



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